Radiotherapy/Experimental Runs/2022-07-26

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Second experimental measurements with Cyberknife at Birmingham. Green scintillator thin sheet measurements only.

Experiment Equipment

Item Notes
Network Hub Set in control room to take output from experimental room ethernet connection. Control laptops connected via 5GHz WiFi.
Control Laptop x3 2 for remote control of CMOS sensor and FPGA, 1 for notes/web GUI.
Ethernet Cable x 3 To connect DAQ laptops to network in the experimental room, network hub to network in control room.
Portable Enclosure Modified Big Zarges Waterproof Wheeled Equipment Case.

Features mount for scintillator stack, front and back openings for beam, patch panel with ports for SHV, BNC, SMA, USB, Camera Link cables.
Hole for sensor powering.
Mylar windows with Al support mounted to internal face: approximately light-tight.

Rev. B Scintillator stack 49 (25 clear, 23 white painted and 1 black painted) X x 100 mm, Y x 100 mm and Z x (approx) 2.8 mm sheets in ascending order from the front/beam of the end of the scintillator. Sheet numbers from front to end (in beam direction gantry angle 270°): 79, 68, 73, 62, 81, 72, 64, 67, 65, 71, 78, 77, 74, 75, 85, 82, 83, 76, 70, 80, 69, 84, 63, 66, 61, 34, 43, 32, 8, 40, 37, 38, 47, 46, 33, 42, 9, 39, 44, 49, 50, 31, 1, 45, 3, 54, 5, 51, 26. Full stack thickness measurements (in mm): 138.12, 137.74, 137.74.
Rev. C Scintillator stack 32 X x 105 mm, Y x 105 mm and Z x (approx) 3 mm sheets (21 3.4 mm and 11 2.0 mm) in ascending order from the front/beam of the end of the scintillator. Sheet numbers from front to end (in beam direction gantry angle 90°): 117, 113, 134, 110, 108, 128, 107, 106, 127, 105, 104, 125, 103, 102, 124, 101, 98, 123, 97, 96, 122, 94, 93, 121, 92, 90, 120, 89, 88, 119, 87, 135. Full stack thickness measurements (in mm): 95.87, 95.96, 95.97.
DAQ laptop x2 Control CMOS sensor and photodiode acquisition.
ISDI CMOS sensor sensor pixel dimension: 1030 x 1536. NO optical grease between scintillator and sensor. Connected to DAQ PC via Camera Link cable.
Nexys Video FPGA development board. For interfacing between DDC232 and PC.
Rev. B Texas Instruments DDC232 custom circuit board (x3) Each housing 16x Hamamatsu S12915-16R photodiodes, coupled directly to scintillator sheets. Aligned by eye to scintillator sheets.
Rev. C Texas Instruments DDC232 custom circuit board (x1) Housing 32x Hamamatsu S12915-16R photodiodes, coupled directly to scintillator sheets. Aligned by eye to scintillator sheets.
Gloves For handling scintillator

Schematic

UCL_Setup.png

Experiment Plan

Rev. B Prototype

  • Background & calibration shoot-throughs (background at all 8 DDC232 full-scale ranges – likely 12.5 pC is most appropriate FSR)
  • Pencil beams, 70-130 MeV, 10 MeV steps, in both directions into stack. For direction with Bragg peak in clear sheets, test 2 currents (high/low)

Rev. C Prototype

  • Background & calibration shoot-throughs (12.5 pC FSR)
  • Pencil beams, 70-110 MeV, 5 MeV steps, at clinical current.

Experiment Notes

Range calorimeter measurements with CMOS sensor + photodiodes.

Images from Sensor: /unix/www/html/pbt/wikiData/images/UCLH_Jun2022/CMOS

Photodiode hexadecimal data: /unix/pbt/data/uclh/20220616/DDC232

Run number Beam Energy (MeV) Estimated Range (mm) Current (nA) Spot size (mm, FWHM) DDC232 FSR (pC) DDC232 Integration Time (us) Degrader WET (mm) Comments Photodiode QB Fit CMOS QB Fit PDL Comparison Replay Fit
0 Background N/A N/A N/A 350 170 0 room light off N/A N/A N/A N/A
1 Background N/A N/A N/A 300 170 0 room light off N/A N/A N/A N/A
2 Background N/A N/A N/A 250 170 0 room light off N/A N/A N/A N/A
3 Background N/A N/A N/A 200 170 0 room light off N/A N/A N/A N/A
4 Background N/A N/A N/A 150 170 0 room light off N/A N/A N/A N/A
5 Background N/A N/A N/A 100 170 0 room light off N/A N/A N/A N/A
6 Background N/A N/A N/A 50 170 0 room light off N/A N/A N/A N/A
7 Background N/A N/A N/A 12.5 170 0 room light off (continued) N/A N/A N/A N/A
8 240 N/A 10 N/A 350 170 50 LH shoot through; 270° gantry; CMOS sensor saturated N/A N/A N/A N/A
9 240 N/A 10 N/A 12.5 170 50 LH shoot through; 270° gantry; CMOS sensor saturated N/A N/A N/A N/A
10 240 N/A 10 N/A 12.5 170 50 RH shoot through; 90° gantry; CMOS sensor saturated N/A N/A N/A N/A
11 200 N/A 90 N/A 12.5 170 50 RH shoot through; 90° gantry; CMOS sensor saturated; N/A N/A N/A N/A
12 200 N/A 20 N/A 12.5 170 50 RH shoot through; 90° gantry; CMOS sensor fine; N/A N/A N/A N/A
13 130 N/A 50 N/A 12.5 170 0 90° gantry; CMOS sensor slight saturation; N/A N/A N/A N/A
14 120 N/A 60 N/A 12.5 170 0 90° gantry; CMOS sensor saturated; N/A N/A N/A N/A
15 120 N/A 270 N/A 12.5 170 0 90° gantry; CMOS sensor saturated; N/A N/A N/A N/A
16 110 N/A 70 N/A 12.5 170 0 90° gantry; CMOS sensor saturated; N/A N/A N/A N/A
17 110 N/A 300 N/A 12.5 170 0 90° gantry; CMOS sensor saturated; N/A N/A N/A N/A
18 100 N/A 90 N/A 12.5 170 0 90° gantry; CMOS sensor saturated; N/A N/A N/A N/A
19 100 N/A 350 N/A 12.5 170 0 90° gantry; CMOS sensor saturated; N/A N/A N/A N/A
20 90 N/A 110 N/A 12.5 170 0 90° gantry; CMOS sensor fine; N/A N/A N/A N/A
21 90 N/A 400 N/A 12.5 170 0 90° gantry; CMOS sensor fine; N/A N/A N/A N/A
22 80 N/A 500 N/A 12.5 170 0 90° gantry; CMOS sensor fine; N/A N/A N/A N/A
23 70 N/A 700 N/A 12.5 170 0 90° gantry; CMOS sensor fine; N/A N/A N/A N/A
24 130 N/A 200 N/A 12.5 170 0 90° gantry; CMOS sensor saturated; N/A N/A N/A N/A
25 200 N/A 20 N/A 12.5 170 50 LH shoot through; 270° gantry; CMOS sensor fine; N/A N/A N/A N/A
26 130 N/A 200 N/A 12.5 170 0 270° gantry; CMOS sensor saturated; N/A N/A N/A N/A
27 120 N/A 270 N/A 12.5 170 0 270° gantry; CMOS sensor saturated; N/A N/A N/A N/A
28 110 N/A 300 N/A 12.5 170 0 270° gantry; CMOS sensor saturated; N/A N/A N/A N/A
29 100 N/A 350 N/A 12.5 170 0 270° gantry; CMOS sensor saturated; N/A N/A N/A N/A
30 90 N/A 400 N/A 12.5 170 0 270° gantry; CMOS sensor saturated; N/A N/A N/A N/A
31 80 N/A 500 N/A 12.5 170 0 270° gantry; CMOS sensor saturated; N/A N/A N/A N/A
32 70 N/A 700 N/A 12.5 170 0 270° gantry; CMOS sensor saturated; N/A N/A N/A N/A
33 background N/A N/A N/A 12.5 170 0 RevC onwards; 270° gantry N/A N/A N/A N/A
34 240 N/A 13 N/A 12.5 170 50 LH shoot through; 270° gantry N/A N/A N/A N/A
35 240 N/A 13 N/A 12.5 170 50 RH shoot through; 90° gantry N/A N/A N/A N/A
36 110 N/A 300 N/A 12.5 170 0 90° gantry; N/A N/A N/A N/A
37 105 N/A 350 N/A 12.5 170 0 90° gantry; N/A N/A N/A N/A
38 100 N/A 350 N/A 12.5 170 0 90° gantry; N/A N/A N/A N/A
39 95 N/A 400 N/A 12.5 170 0 90° gantry; N/A N/A N/A N/A
40 90 N/A 400 N/A 12.5 170 0 90° gantry; N/A N/A N/A N/A
41 85 N/A 500 N/A 12.5 170 0 90° gantry; N/A N/A N/A N/A
42 80 N/A 500 N/A 12.5 170 0 90° gantry; N/A N/A N/A N/A
43 75 N/A 700 N/A 12.5 170 0 90° gantry; N/A N/A N/A N/A
44 70 N/A 700 N/A 12.5 170 0 90° gantry; N/A N/A N/A N/A